Acyclic modular flowsheet optimization using multiple trust regions and Gaussian process regression

Published in Computer Aided Chemical Engineering, 2021

Recommended citation: Medina, E.S., Vallejo, D.R., Chachuat, B., Sundmacher, K., Petsagkourakis, P. and del Rio-Chanona, E.A., 2021. Acyclic modular flowsheet optimization using multiple trust regions and Gaussian process regression. In Computer Aided Chemical Engineering (Vol. 50, pp. 1117-1123). Elsevier. https://doi.org/10.1016/B978-0-323-88506-5.50172-8

Here, we present an algorithm to optimize process flowsheets using Gaussian processes regression and trust regions.